Anti-Phospho-SHIP Antibody, Polyclonal
Rabbit polyclonal antibody against human, mouse phosphoSHIP
产品描述
- Phospho-SHIP is highly phosphorylated form of SHIP. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human tyrosine phosphorylated SHIP.
- Components:
Subtype:
一抗
Target Antigen:
PhosphoSHIP
Reactive Species:
人; 小鼠
Conjugation:
未结合
Host Species:
兔
Cell Type:
粒细胞及其亚型; 淋巴细胞; 髓系细胞
Application:
流式细胞术; 免疫印迹; 免疫荧光; 免疫沉淀
Area of Interest:
免疫学
Clone:
Not applicable
Gene ID:
3635 (human), 16331 (mouse)
Isotype:
Not applicable
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