StemSpan™ Megakaryocyte ExpansionSupplement (100X)
Product Overview:
StemSpan™Megakaryocyte Expansion Supplement (100X) (formerly known as CC220) contains acombination of recombinant human cytokines (SCF, IL-6, IL-9 and TPO) formulatedto selectively promote the expansion and differentiation of human megakaryocyteprogenitor cells from CD34+ cells isolated from human cord blood (CB) or bonemarrow samples. The Megakaryocyte Expansion Supplement is intended for use incombination with StemSpan™ SFEM, SFEM II and -ACF serum-free expansion media,or any other media for culturing human hematopoietic cells.
When added to serum-free medium, the Megakaryocyte Expansion Supplementtypically promotes the production of hundreds of megakaryocytes per input CD34+cell in 14-day liquid cultures initiated with CD34+ human CB cells. See datatab for more details.
This product is recommended for:
• Research into the regulation of megakaryocytopoiesis
• Development of procedures to expand megakaryocytes and platelets in culture
Advantages:
• Formulated to produce large numbers ofhuman megakaryocytes in liquid cultures initiated with CD34+ CB or BM cells.
• Optimized for use with StemSpan™ media. When combined with StemSpan™ SFEM IIin particular, supports up to 2-fold higher expansion of megakaryocytes fromhuman CD34+ CB cells than other serum-free media on the market.
• Supplied as a 100X concentrate. After thawing and mixing, the tube contentscan be added directly to any hematopoietic cell expansion medium of choice.
Contains:
• Recombinant human stem cell factor (SCF)
• Recombinant human interleukin 6 (IL-6)
• Recombinant human interleukin 9 (IL-9)
• Recombinant human thrombopoietin (TPO)
Subtype:
添加物
Cell Type:
造血干细胞和祖细胞; 巨核细胞
Species:
人
Application:
细胞培养; 分化; 扩增
Brand:
StemSpan
Area of Interest:
干细胞生物学; 移植研究
Formulation:
无血清; 成分确定
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