Overview
ImmunoCult™ Human CD3/CD28/CD2 T Cell Activator is designed to activate and expand human T cells in the absence of magnetic beads, feeder cells or antigen. ImmunoCult™ Human CD3/CD28/CD2 T Cell Activator consists of soluble tetrameric antibody complexes that bind CD3, CD28 and CD2 cell surface ligands. Binding of the tetrameric antibody complexes results in the cross-linking of CD3, CD28, and CD2 cell surface ligands, thereby providing the required primary and co-stimulatory signals for T cell activation. Activated T cells can be expanded in ImmunoCult™-XF T Cell Expansion Medium or other media for culturing human T cells supplemented with cytokines.
Advantages:
• Robust activation and expansion of human T cells without the use of magnetic beads, feeder cells, or antigen
• Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells
• Highly stable, filter-sterilized soluble reagent
Contains:
• Anti-human CD3 monospecific tetrameric antibody complex
• Anti-human CD28 monospecific tetrameric antibody complex
• Anti-human CD2 monospecific tetrameric antibody complex
Cell Type:
T细胞; CD4+T细胞; CD8+T细胞
Area of Interest:
免疫学; T细胞工程