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Anti-Hu CD73, AD2, BT, 50µg 
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2434.00
2434.0
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品牌: StemCell 型号: 60044BT
规格: 50 µg

Stemcell  60044BT  Anti-Human CD73 (Ecto-5'-Nucleotidase) Antibody, Clone AD2

Product Overview

The AD2 antibody reacts with human CD73, a glycosyl phosphatidylinositol (GPI)-anchored glycoprotein and ecto-5’-nucleotidase expressed on the surface of subsets of B and T cells, follicular dendritic cells, mesenchymal stem cells, endothelial cells and epithelial cells. CD73 catalyzes the hydrolysis of 5’-adenosine monophosphate (AMP) to form the bioactive nucleoside, adenosine, and plays a pivotal role in the activation of P1 adenosine receptors by regulating extracellular adenosine concentrations. CD73 also appears to function as a co-signaling molecule on T cells and as an adhesion molecule mediating lymphocyte interactions with the endothelium and follicular dendritic cells. CD73 is used as a marker for lymphocyte differentiation, its expression increasing during development. It is also a useful marker for identifying undifferentiated mesenchymal stem cells. CD73 is highly expressed in many types of human and mouse cancers and has been implicated in the control of tumor growth.

Subtype:一抗

Target Antigen:CD73

Reactive Species:黑猩猩; 人; 恒河猴; 猕猴

Conjugation:APC; 生物素; FITC; PE; 未结合

Host Species:小鼠

Cell Type:间充质干细胞和祖细胞

Application:流式细胞术; 免疫荧光; 免疫组化

Area of Interest:干细胞生物学

Clone:AD2

Gene ID:4907

Isotype:IgG1, kappa

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