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Anti-Hu CD43, CD43-10G7, AZ, 25t 
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1554.00
1554.0
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品牌: StemCell 型号: 60085AZ.1
规格: 25 tests

Stemcell  60085AZ.1  Anti-Human CD43 Antibody, Clone CD43-10G7

Product Overview

The CD43-10G7 antibody reacts with human CD43, a type I transmembrane sialoglycoprotein expressed on the surface of most human hematopoietic cells, including thymocytes, peripheral T cells, NK cells, monocytes, granulocytes, some B cells (activated B cells and an early B cell subset in bone marrow), plasma cells, and hematopoietic progenitor cells. Low expression levels are observed on platelets. CD43 exhibits different glycoforms in the range of ~95 - 135 kDa, depending on the cell type. It binds ligands such as CD54 and CD169 (Siglec-1) and plays regulatory roles in cell adhesion and activation, apoptosis and tumor progression, and is used a marker for discriminating normal from neoplastic T cells and B cells within tissues. Binding of the CD43-10G7 antibody to CD43 on neutrophils reportedly induces homotypic cell adhesion.

Subtype:一抗

Target Antigen:CD43

Reactive Species:

Conjugation:APC; PE; 未结合

Host Species:小鼠

Cell Type:B细胞

Application:流式细胞术; 功能检测; 免疫沉淀

Area of Interest:免疫学

Clone:CD43-10G7

Gene ID:6693

Isotype:IgG1, kappa

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